Oxygen is required by every cell of the body to carry out essential functions including repair and metabolism. Ozone (O3) is one of the purest forms of oxygen, and ozone therapy involves the introduction of ozone gas into the body. Ozone is usually administered through an intravenous injection, topical application, or rectal insufflation. Ozone therapy promotes self-healing as it is entirely natural. Its power is especially noticeable in treating conditions involving tissue damage such as arthritis, wound and deep scar healing, certain infections, and skin disorders while overall stimulating the immune system to enhance immune responses.